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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512289Generated: October 30, 2026

2,3-Dichlorobenzoic acid → 2,3-dichloro-N-((4-(2-(trifluoromethyl)pyrimidin-5-yl)tetrahydro-2H-pyran-4-yl)methyl)benzamide

https://huagongshe.com/reaction/512289

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Dichlorobenzoic acidHCID 5765—
Reactant(4-(2-(trifluoromethyl)pyrimidin-5-yl)tetrahydro-2H-pyran-4-yl)methanamineHCID 86716336—
Product2,3-dichloro-N-((4-(2-(trifluoromethyl)pyrimidin-5-yl)tetrahydro-2H-pyran-4-yl)methyl)benzamideHCID 86716335—

Reaction Steps

From 2,3-dichlorobenzoic acid and (4-(2-(trifluoromethyl)pyrimidin-5-yl)tetrahydro-2H-pyran-4-yl)methanamine. LCMS (MH+): m/z=434.1, tR (minutes, Method F)=2.34

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-cda0424ce7d446149b61b9e7e72274ab
Source noteuspto-grants-2015_08