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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512294Generated: October 29, 2026

2-Chloro-3-methoxybenzoic acid → 2-chloro-N-(3-cyclopropyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propyl)-3-methoxybenzamide

https://huagongshe.com/reaction/512294

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-3-methoxybenzoic acidHCID 16218063—
Reactant2-(2-Trifluoromethyl-pyrimidin-5-yl)-3-cyclopropyl-propylamineHCID 86716315—
Product2-chloro-N-(3-cyclopropyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propyl)-3-methoxybenzamideHCID 86716342—

Reaction Steps

From 2-chloro-3-methoxybenzoic acid and 3-cyclopropyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propan-1-amine. LCMS (MH+): m/z=414.0, tR (minutes, Method F)=2.53

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-622716369e064abf9b6f11da88a49481
Source noteuspto-grants-2015_08