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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512295Generated: October 30, 2026

3-Methoxy-2-MethylBenzoic Acid → 2-methyl-N-(3-cyclopropyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propyl)-3-methoxybenzamide

https://huagongshe.com/reaction/512295

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methoxy-2-MethylBenzoic AcidHCID 7021483—
Reactant2-(2-Trifluoromethyl-pyrimidin-5-yl)-3-cyclopropyl-propylamineHCID 86716315—
Product2-methyl-N-(3-cyclopropyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propyl)-3-methoxybenzamideHCID 86716343—

Reaction Steps

From 2-methyl-3-methoxybenzoic acid and 3-cyclopropyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propan-1-amine. LCMS (MH+): m/z=394.0, tR (minutes, Method F)=2.59

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-d1dd712004c44abd945e8a4a49f93209
Source noteuspto-grants-2015_08