2,3-Dichlorobenzoic acid → HCID 86716344, compound

HRID 512296Notes

Reaction equation

HRID 512296 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:12][C:13]1([CH2:16][CH:17]([C:20]2[CH:21]=[N:22][C:23]([C:26]([F:29])([F:28])[F:27])=[CH:24][CH:25]=2)[CH2:18][NH2:19])[CH2:15][CH2:14]1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:19][CH2:18][CH:17]([C:20]1[CH:21]=[N:22][C:23]([C:26]([F:29])([F:27])[F:28])=[CH:24][CH:25]=1)[CH2:16][C:13]1([F:12])[CH2:15][CH2:14]1)=[O:6]

Participants

3

Reactant 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716345HCID 86716345, compound

Product 1

HCID 86716344HCID 86716344, compound

Procedure

From 2,3-dichlorobenzoic acid and 3-(1-fluorocyclopropyl)-2-(6-(trifluoromethyl)pyridin-3-yl)propan-1-amine. LCMS (MH+): m/z=435.1, tR (minutes, Method G)=2.46

Sources & evidence

ORD record
ord-cd2e94afd5504ce49828a690540a7787
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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