2,3-Dichlorobenzoic acid → HCID 86716348, compound

HRID 512300Notes

Reaction equation

HRID 512300 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:12][C:13]1([CH2:16][CH:17]([N:20]2[CH:25]=[CH:24][C:23]([C:26]([F:29])([F:28])[F:27])=[N:22][CH2:21]2)[CH2:18][NH2:19])[CH2:15][CH2:14]1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:19][CH2:18][CH:17]([N:20]1[CH:25]=[CH:24][C:23]([C:26]([F:29])([F:28])[F:27])=[N:22][CH2:21]1)[CH2:16][C:13]1([F:12])[CH2:14][CH2:15]1)=[O:6]

Participants

3

Reactant 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716349HCID 86716349, compound

Product 1

HCID 86716348HCID 86716348, compound

Procedure

From 2,3-dichlorobenzoic acid and 3-(1-fluorocyclopropyl)-2-(6-(trifluoromethyl)pyrimidin-3-yl)propan-1-amine. LCMS (MH+): m/z=436.1, tR (minutes, Method G)=2.61

Sources & evidence

ORD record
ord-9c03e326e6e747aa9e1f19637304fe7e
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

Loading…