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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512307Generated: October 29, 2026

2-Chloro-3-fluorobenzoic acid → (+)-2-chloro-3-fluoro-N-(3-cyclopropyl-2-methyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propyl)benzamide

https://huagongshe.com/reaction/512307

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-3-fluorobenzoic acidHCID 302620—
Reactant3-Cyclopropyl-2-methyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propan-1-amineHCID 86716324—
Product(+)-2-chloro-3-fluoro-N-(3-cyclopropyl-2-methyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propyl)benzamideHCID 86716325—

Reaction Steps

From 2-chloro-3-fluorobenzoic acid and 3-cyclopropyl-2-methyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propan-1-amine. LCMS (MH+): m/z=416.1, tR (minutes, Method G)=2.48

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-3c1fa2280056422eb0bd146ed9d7f6a7
Source noteuspto-grants-2015_08