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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512349Generated: November 3, 2026

2-Chloro-3-methoxybenzoic acid → 2-chloro-3-methoxy-N-(3-cyclopropyl-2-(6-(difluoromethyl)pyridin-3-yl)propyl)benzamide

https://huagongshe.com/reaction/512349

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-3-methoxybenzoic acidHCID 16218063—
Reactant3-Cyclopropyl-2-(6-(difluoromethyl)pyridin-3-yl)propan-1-amineHCID 86716400—
Product2-chloro-3-methoxy-N-(3-cyclopropyl-2-(6-(difluoromethyl)pyridin-3-yl)propyl)benzamideHCID 86716403—

Reaction Steps

From 2-chloro-3-methoxybenzoic acid and 3-cyclopropyl-2-(6-(difluoromethyl)pyridin-3-yl)propan-1-amine. LCMS (MH+): m/z=395.1, tR (minutes, Method F)=2.96

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-6be8b847e55f4b27949a7fe3c314015a
Source noteuspto-grants-2015_08