2,3-Dichlorobenzoic acid → HCID 86716406, compound

HRID 512352Notes

Reaction equation

HRID 512352 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:12][C:13]1([F:27])[CH2:18][CH2:17][C:16]([CH2:25][NH2:26])([N:19]2[CH:23]=[C:22]([CH3:24])[N:21]=[CH:20]2)[CH2:15][CH2:14]1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:26][CH2:25][C:16]1([N:19]2[CH:23]=[C:22]([CH3:24])[N:21]=[CH:20]2)[CH2:17][CH2:18][C:13]([F:12])([F:27])[CH2:14][CH2:15]1)=[O:6]

Participants

3

Reactant 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716191HCID 86716191, compound

Product 1

HCID 86716406HCID 86716406, compound

Procedure

From 2,3-dichlorobenzoic acid and (4,4-difluoro-1-(4-methyl-1H-imidazol-1-yl)cyclohexyl)methanamine. LCMS (MH+): m/z=402.0, tR (minutes, Method E)=0.45

Sources & evidence

ORD record
ord-6616519bb7854338ba5eaaf3241f5464
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

Loading…