2,3-Dichlorobenzoic acid → HCID 86716407, compound

HRID 512353Notes

Reaction equation

HRID 512353 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[Br:12][C:13]1[N:18]=[CH:17][C:16]([C:19]2([CH:27]([NH2:29])[CH3:28])[CH2:24][CH2:23][C:22]([F:26])([F:25])[CH2:21][CH2:20]2)=[CH:15][CH:14]=1>>[Br:12][C:13]1[N:18]=[CH:17][C:16]([C:19]2([CH:27]([NH:29][C:4](=[O:6])[C:3]3[CH:7]=[CH:8][CH:9]=[C:10]([Cl:11])[C:2]=3[Cl:1])[CH3:28])[CH2:20][CH2:21][C:22]([F:25])([F:26])[CH2:23][CH2:24]2)=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716408HCID 86716408, compound

Product 1

HCID 86716407HCID 86716407, compound

Procedure

From 2,3-dichlorobenzoic acid and 1-(1-(6-bromopyridin-3-yl)-4,4-difluorocyclohexyl)ethanamine. LCMS (MH+): m/z=493.1, tR (minutes, Method D)=0.83

Sources & evidence

ORD record
ord-fba539643b844a50bcf558ce549b34f0
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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