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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512360Generated: November 1, 2026

3-Chloro-2-fluorobenzoic acid → 3-chloro-N-(3-cyclopropyl-2-(6-(trifluoromethyl)pyridin-3-yl)propyl)-2-fluorobenzamide

https://huagongshe.com/reaction/512360

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-2-fluorobenzoic acidHCID 302931—
Reactant3-Cyclopropyl-2-(6-trifluoromethyl-pyridin-3-yl)-propylamineHCID 86716284—
Product3-chloro-N-(3-cyclopropyl-2-(6-(trifluoromethyl)pyridin-3-yl)propyl)-2-fluorobenzamideHCID 86716414—

Reaction Steps

From 3-chloro-2-fluorobenzoic acid and 3-cyclopropyl-2-(6-(trifluoromethyl)pyridin-3-yl)propan-1-amine. LCMS (MH+): m/z=401.2, tR (minutes, Method D)=0.84

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-14fb854091884242bf2bbb71ef0fc72a
Source noteuspto-grants-2015_08