2-Chloro-3-fluorobenzoic acid → HCID 86716426, compound

HRID 512371Notes

Reaction equation

HRID 512371 reaction equation
[Cl:1][C:2]1[C:10]([F:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[C:12]1([CH:18]([C:21]2[CH:22]=[N:23][C:24]([C:27]([F:30])([F:29])[F:28])=[CH:25][CH:26]=2)[CH2:19][NH2:20])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[Cl:1][C:2]1[C:10]([F:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:20][CH2:19][CH:18]([C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)[C:21]1[CH:22]=[N:23][C:24]([C:27]([F:30])([F:28])[F:29])=[CH:25][CH:26]=1)=[O:6]

Participants

3

Reactant 2

HCID 3026202-Chloro-3-fluorobenzoic acidHCID 86716422HCID 86716422, compound

Product 1

HCID 86716426HCID 86716426, compound

Procedure

From 2-chloro-3-fluorobenzoic acid and 2-phenyl-2-(6-(trifluoromethyl)pyridin-3-yl)ethanamine. LCMS (N I+): m/z=423.1, tR (minutes, Method D)=0.81

Sources & evidence

ORD record
ord-4e720a6477b74c2683b4334906bb31fa
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

Loading…