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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512374Generated: October 30, 2026

2-Chlorobenzoic Acid → 2-Chloro-N-(2-(tetrahydro-2H-pyran-4-yl)-2-(6-(trifluoromethyl)pyridin-3-yl)ethyl)benzamide

https://huagongshe.com/reaction/512374

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chlorobenzoic AcidHCID 8374—
Reactant2-(Tetrahydro-2H-pyran-4-yl)-2-(6-(trifluoromethyl)pyridin-3-yl)ethanamineHCID 86716201—
Product2-Chloro-N-(2-(tetrahydro-2H-pyran-4-yl)-2-(6-(trifluoromethyl)pyridin-3-yl)ethyl)benzamideHCID 86716430—

Reaction Steps

From 2-chlorobenzoic acid and 2-(tetrahydro-2H-pyran-4-yl)-2-(6-(trifluoromethyl)pyridin-3-yl)ethanamine. LCMS (MH+): m/z=413.0, tR (minutes, Method E)=0.64

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-1e97500be4ba4c199e3ae5cac744bb84
Source noteuspto-grants-2015_08