2,3-Dichlorobenzoic acid → HCID 86716436, compound

HRID 512380Notes

Reaction equation

HRID 512380 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:12][N:13]1[CH:17]=[C:16]([CH:18]([C:21]2[CH:22]=[N:23][C:24]([C:27]([F:30])([F:29])[F:28])=[CH:25][CH:26]=2)[CH2:19][NH2:20])[CH:15]=[N:14]1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:20][CH2:19][CH:18]([C:16]1[CH:15]=[N:14][N:13]([CH3:12])[CH:17]=1)[C:21]1[CH:22]=[N:23][C:24]([C:27]([F:30])([F:28])[F:29])=[CH:25][CH:26]=1)=[O:6]

Participants

3

Reactant 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716437HCID 86716437, compound

Product 1

HCID 86716436HCID 86716436, compound

Procedure

From 2,3-dichlorobenzoic acid and 2-(1-methyl-1H-pyrazol-4-yl)-2-(6-(trifluoromethyl)pyridin-3-yl)ethanamine. LCMS (MH+): m/z=443.2, tR (minutes, Method D)=0.67

Sources & evidence

ORD record
ord-a573a80291f64341856f605d05287b96
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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