2-Chloro-3-methoxybenzoic acid → HCID 86716438, compound

HRID 512381Notes

Reaction equation

HRID 512381 reaction equation
[Cl:1][C:2]1[C:10]([O:11][CH3:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:13][C:14]1([F:32])[CH2:19][CH2:18][C:17]([CH2:30][NH2:31])([C:20]2[CH:21]=[N:22][C:23]([C:26]([F:29])([F:28])[F:27])=[N:24][CH:25]=2)[CH2:16][CH2:15]1>>[Cl:1][C:2]1[C:10]([O:11][CH3:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:31][CH2:30][C:17]1([C:20]2[CH:21]=[N:22][C:23]([C:26]([F:29])([F:28])[F:27])=[N:24][CH:25]=2)[CH2:18][CH2:19][C:14]([F:13])([F:32])[CH2:15][CH2:16]1)=[O:6]

Participants

3

Reactant 2

HCID 162180632-Chloro-3-methoxybenzoic acidHCID 86716351(4,4-Difluoro-1-(2-(trifluoromethyl)pyrimidin-5-yl)cyclohexyl)methanamine

Product 1

HCID 86716438HCID 86716438, compound

Procedure

From 2-chloro-3-methoxybenzoic acid and [4,4-Difluoro-1-(2-(trifluoromethyl)pyrimidin-5-yl)cyclohexyl]methanamine. LCMS (MH+): m/z=464.1, tR (minutes, Method F)=3.02

Sources & evidence

ORD record
ord-fd3d1f0b87cc4c36bcdfbadc8d81c7fa
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

Loading…