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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512388Generated: October 30, 2026

2,6-Dichlorobenzoic acid → 2,6-dichloro-N((4,4-difluoro-1-(2-(difluoromethyl)pyrimidin-5-yl)cyclohexyl)methyl)benzamide

https://huagongshe.com/reaction/512388

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dichlorobenzoic acidHCID 5758—
Reactant(1-(2-(Difluoromethyl)pyrimidin-5-yl)-4,4-difluorocyclohexyl)methanamineHCID 86716443—
Product2,6-dichloro-N((4,4-difluoro-1-(2-(difluoromethyl)pyrimidin-5-yl)cyclohexyl)methyl)benzamideHCID 73673065—

Reaction Steps

From 2,6-dichlorobenzoic acid and (1-(2-(difluoromethyl)pyrimidin-5-yl)-4,4-difluorocyclohexyl)methanamine. LCMS (MH+): m/z=450.1, tR (minutes, Method F)=2.93

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-fcf96c96a1534c32a5befa128835ca02
Source noteuspto-grants-2015_08