2-Chlorobenzoic Acid → HCID 86716446, compound

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Reaction Steps

The racemic mixture which was prepared in a similar manner to example 3a from 2-chlorobenzoic acid and 2-(2-methyl-pyrimidin-5-yl)-3-(1-trifluoromethyl-cycl opropyl)-propylamine was separated into the two enantiomers by preparative SFC to yield the title compound. LCMS (MH+): m/z=398.1, tR (minutes, Method F)=2.55. [α]D20=−25.5 (c=5.1 mg/mL,CHCl3)

Provenance & Evidence