2,3-Dichlorobenzoic acid → HCID 86716358, compound

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Reaction Steps

The racemic mixture which was prepared in a similar manner to example 3a from 2,3-dichlorobenzoic acid and 2-(2-methylpyrimidin-5-yl)-2-(tetrahydro-2H-pyran-4-yl)ethanamine was separated into the two enantiomers by preparative SFC to yield the title compound LCMS (MH+): m/z=394.1, tR (minutes, Method F)=1.88. [α]D20=+57.50 (c=2.0 mg/mL,CHCl3)

Provenance & Evidence