2-Chlorobenzoic Acid → HCID 86716366, compound

Participants

Reaction Steps

The racemic mixture which was prepared in a similar manner to example 3a from 2-chlorobenzoic acid and 3-(1-(trifluoromethyl)cyclopropyl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)propan-1-amine was separated into the two enantiomers by preparative SFC to yield the title compound. LCMS (MH+): m/z=452.0, tR (minutes, Method F)=3.03. [α]D20=+27.50 (c=4.80 mg/mL,CHCl3)

Provenance & Evidence