2-Chlorobenzoic Acid → HCID 86716377, compound

Participants

Reaction Steps

The racemic mixture which was prepared in a similar manner to example 3a from 2-chlorobenzoic acid and 2-(4-fluorophenyl)-2-(6-(trifluoromethyl)pyridin-3-yl)ethanamine was separated into the two enantiomers by preparative SFC to yield the title compound. LCMS (MH+): m/z=423.1, tR (minutes, Method G)=2.58. [α]D20=+18.1 (c=5.22 mg/mL,CHCl3) And the corresponding enantiomer

Provenance & Evidence