2-Chlorobenzoic Acid → HCID 86716390, compound

Participants

Reaction Steps

The racemic mixture which was prepared in a similar manner to example 3a from 2-chlorobenzoic acid and 2-(4,4-difluorocyclohexyl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethanamine was separated into the two enantiomers by preparative SFC to yield the title compound. LCMS (MH+): m/z=448.1, tR (minutes, Method F)=2.95. [α]D20==+28.00 (c=1.5 mg/mL,CHCl3)

Provenance & Evidence