2,3-Dichlorobenzoic acid → HCID 86716361, compound

Participants

Reaction Steps

The racemic mixture which was prepared in a similar manner to example 3a from 2,3-dichlorobenzoic acid and 2-(4,4-difluorocyclohexyl)-2-(2-methylpyrimidin-5-yl)ethanamine was separated into the two enantiomers by preparative SFC to yield the title compound. LCMS (MH+): m/z=448.1, tR (minutes, Method F)=2.95. [α]D20=+49.6 (c=4.8 mg/mL,CHCl3)

Provenance & Evidence