2-Chlorobenzoic Acid → HCID 86716447, compound

Participants

Reaction Steps

The racemic mixture which was prepared in a similar manner to example 3a from 2-chlorobenzoic acid and 2-(2-(difluoromethyl)pyrimidin-5-yl)-3-(1-fluorocyclopropyl)propan-1-amine was separated into the two enantiomers by preparative SFC to yield the title compound. LCMS (MH+): m/z=384.1, tR (minutes, Method F)=2.72. [α]D20=+21.30 (c=2.39 mg/mL,CHCl3)

Provenance & Evidence