2,3-Dichlorobenzoic acid → HCID 86716450, compound

Participants

Reaction Steps

The racemic mixture which was prepared in a similar manner to example 3a from 2,3-dichlorobenzoic acid and 2-(2-(difluoromethyl)pyrimidin-5-yl)-3-(1-fluorocyclopropyl)propan-1-amine was separated into the two enantiomers by preparative SFC to yield the title compound. LCMS (MH+): m/z=418.1, tR (minutes, Method F)=2.89. [α]D20=+21.70 (c=3.00 mg/mL,CHCl3)

Provenance & Evidence