2-Chlorobenzoic Acid → HCID 86716451, compound

Participants

Reaction Steps

The racemic mixture which was prepared in a similar manner to example 3a from 2-chlorobenzoic acid and 2-(2-(difluoromethyl)pyrimidin-5-yl)-3-(1-(trifluoromethyl)cyclopropyl)propan-1-amine was separated into the two enantiomers by preparative SFC to yield the title compound. LCMS (MH+): m/z=434.0, tR (minutes, Method F)=2.42. [α]D20=+25.30 (c=3.75 mg/mL,CHCl3)

Provenance & Evidence