2,3-Dichlorobenzoic acid → HCID 86716454, compound

Participants

Reaction Steps

The racemic mixture which was prepared in a similar manner to example 3a from 2,3-dichlorobenzoic acid and 2-(2-(difluoromethyl)pyrimidin-5-yl)-3-(1-(trifluoromethyl)cyclopropyl)propan-1-amine was separated into the two enantiomers by preparative SFC to yield the title compound. LCMS (MH+): m/z=468.0, tR (minutes, Method F)=2.84. [α]D20=+27.80 (c=3.41 mg/mL,CHCl3)

Provenance & Evidence