HuagongsheHuagongshe Chemistry Print Report · For research reference only
Veratrole → N-Boc-(2,3-dimethoxyphenyl)-4-piperidinylmethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Veratrole | HCID 7043 | — |
| Reactant | 4-(Methoxymethylcarbamoyl)piperidine-1-carboxylic acid tert-butyl ester | HCID 44203202 | — |
| Product | N-Boc-(2,3-dimethoxyphenyl)-4-piperidinylmethanone | HCID 46780868 | — |
Reaction Steps
In Scheme G, step c, 4-[(methoxymethylamino)carbonyl]-1-piperidinecarboxylic acid, 1,1-dimethylethyl ester (15) is reacted with lithiated veratrole to give 4-(2,3-dimethoxybenzoyl)-1-piperidinecarboxylic acid, 1,1-dimethylethyl ester (7).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06713627B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-a83037a88ba6440c954c089e1f0e2181 |
| Source note | uspto-grants-2004_03 |