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HRID512487

反应详情

EQUATION

反应方程式

HRID 512487 的结构方程式

REACTANTS

反应物

4
结构：OB(O)c1ccccc1C(F)F
HCID44717243

[2-(Difluoromethyl)phenyl]boronic acid

C7H7BF2O2

结构：Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)O)cn1Cc1ccc(C#N)cc1
HCID86711527

未命名化合物

结构：Cc1c(Br)c(=O)c(C(=O)O)cn1Cc1ccc(C#N)cc1
HCID86711528

未命名化合物

结构：Cc1c(Br)c(=O)c(C(=O)O)cn1C(C)c1ccc(C#N)cc1
HCID86711530

未命名化合物

PRODUCTS

生成物

1
结构：Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)O)cn1C(C)c1ccc(C#N)cc1
HCID86711529

未命名化合物

PROCEDURE

实验过程

Preparation 3 is prepared following the procedure described for preparation 1d, substituting 3-(trifluoromethyl)phenylboronic acid with 2-(difluoromethyl)phenylboronic acid and substituting preparation 1c with preparation 2b as starting material. ESI mass spectrum: [M+H]+=409; Retention time HPLC: 1.00 min (Z018_S04).

WORKUP

后处理

  1. customPreparation 3
  2. customis prepared
  3. custom1.00 min (Z018_S04)