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HRID512496

反应详情

EQUATION

反应方程式

HRID 512496 的结构方程式

REACTANTS

反应物

3
结构：BrBr
HCID24408

Bromine

Br2

结构：CS(=O)(=O)c1ccc(CN)cc1.Cl
HCID2729269

1-[4-(Methanesulfonyl)phenyl]methanamine--hydrogen chloride (1/1)

C8H12ClNO2S

结构：Cc1c(Br)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1Cc1ccc(C#N)cc1
HCID86711536

未命名化合物

PRODUCTS

生成物

1
结构：Cc1c(Br)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1C(C)c1ccc(C#N)cc1
HCID86711538

未命名化合物

PROCEDURE

实验过程

5-Bromo-1-(4-cyano-benzyl)-6-methyl-4-oxo-1,4-dihydro-pyridine-3-carboxylic acid 4-methanesulfonyl-benzylamide can be prepared as described for preparation 9, substituting methylamine with 4-methylsulfonylbenzylamine hydrochloride; ESI mass spectrum: [M+H]+=528 (bromine isotope pattern); Retention time HPLC: 0.95 min (Z018_S04).

WORKUP

后处理

  1. customas described for preparation 9
  2. custom0.95 min (Z018_S04)