HCID 86711550, compound → HCID 86711549, compound

HRID 512510Notes

Reaction equation

HRID 512510 reaction equation
[CH3:1][NH:2]C(C1C(=O)C(C2C=CN=C(C(F)(F)F)C=2)=C(C)N(C(C2C=CC(Br)=CN=2)C)C=1)=O.[CH3:32][NH:33][C:34]([C:36]1[C:41](=[O:42])[C:40]([C:43]2[CH:48]=[CH:47][CH:46]=[C:45]([CH:49]([F:51])[F:50])[CH:44]=2)=[C:39]([CH3:52])[N:38]([CH:53]([C:55]2[CH:60]=[CH:59][C:58](Br)=[CH:57][N:56]=2)[CH3:54])[CH:37]=1)=[O:35]>>[CH3:32][NH:33][C:34]([C:36]1[C:41](=[O:42])[C:40]([C:43]2[CH:48]=[CH:47][CH:46]=[C:45]([CH:49]([F:51])[F:50])[CH:44]=2)=[C:39]([CH3:52])[N:38]([CH:53]([C:55]2[CH:60]=[CH:59][C:58]([C:1]#[N:2])=[CH:57][N:56]=2)[CH3:54])[CH:37]=1)=[O:35]

Participants

3

Reactant 2

HCID 86711550HCID 86711550, compoundHCID 86711551HCID 86711551, compound

Product 1

HCID 86711549HCID 86711549, compound

Procedure

Example 16 is prepared as described for Example 15, substituting preparation 15b with preparation 16c. ESI mass spectrum: [M+H]+=423; Retention time HPLC: 0.94 min (Z018_S04).

Workup

  1. customExample 16 is prepared
  2. custom0.94 min (Z018_S04)

Sources & evidence

ORD record
ord-bb73c436babc4b5bbfa84d907cfb5bb5
Source dataset
uspto-grants-2015_08
Patent number
US09102624B2

Reaction notes

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