反应详情

温度

80 °C

A mixture of 2-naphthalenyl isothiocyanate (0.5 g, 2.7 mmol) and ethyl 2-amino-2-cyanoacetate (0.38 g, 2.97 mmol) in EtOH (16 mL) was heated at 80° C. for 3 h. The reaction mixture was cooled to rt, and the solvent was concentrated in vacuo. The resulting solids were collected and washed with n-Hexane-EtOAc (1:1) to give 565 mg (67% yield) of the titled compound.

1. temperatureThe reaction mixture was cooled to rt
2. concentrationthe solvent was concentrated in vacuo
3. customThe resulting solids were collected
4. washwashed with n-Hexane-EtOAc (1:1)