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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512690Generated: October 27, 2026

2-Thiopheneboronic acid → 2-(4-Bromo-3,5-dimethoxyphenyl)thiophene

https://huagongshe.com/reaction/512690

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneboronic acidHCID 2733960—
Reactant2-Bromo-5-iodo-1,3-dimethoxybenzeneHCID 58432078—
Product2-(4-Bromo-3,5-dimethoxyphenyl)thiopheneHCID 58432009—

Reaction Steps

2-(4-Bromo-3,5-dimethoxyphenyl)thiophene was prepared from 2-bromo-5-iodo-1,3-dimethoxybenzene and thiophen-2-ylboronic acid according to the procedure used in Example 12. Purification by chromatography (0-10% EtOAc-hexanes) gave a yellow solid (0.624 g, 55% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102643B2
Source datasetuspto-grants-2015_08
ORD IDord-9272669fea454486874969401742d08a
Source noteuspto-grants-2015_08