4-Methylpyrazole → HCID 76332839, compound

HRID 512840Notes

Reaction equation

HRID 512840 reaction equation
[CH3:1][C:2]1[CH:3]=[N:4][NH:5][CH:6]=1.Cl[C:8]1[N:9]=[N:10][C:11](Cl)=[CH:12][CH:13]=1.[F:15][C:16]1[CH:24]=[C:23]2[C:19]([CH2:20][CH2:21][N:22]2[CH:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)=[CH:18][CH:17]=1>>[F:15][C:16]1[CH:24]=[C:23]2[C:19]([CH2:20][CH2:21][N:22]2[CH:25]2[CH2:30][CH2:29][N:28]([C:8]3[N:9]=[N:10][C:11]([N:4]4[CH:3]=[C:2]([CH3:1])[CH:6]=[N:5]4)=[CH:12][CH:13]=3)[CH2:27][CH2:26]2)=[CH:18][CH:17]=1

Participants

4

Procedure

The title compound was prepared following the procedure as described in Example 14, reacting 4-methylpyrazole, 3,6-dichloropyridazine, and 6-fluoro-1-(piperidin-4-yl)indoline.

Sources & evidence

ORD record
ord-f038dab5f1804dbc83846d20ffa4bcd5
Source dataset
uspto-grants-2015_08
Patent number
US09102669B2

Reaction notes

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