4-Methylpyrazole → HCID 76332839, compound
Reaction equation
[CH3:1][C:2]1[CH:3]=[N:4][NH:5][CH:6]=1.Cl[C:8]1[N:9]=[N:10][C:11](Cl)=[CH:12][CH:13]=1.[F:15][C:16]1[CH:24]=[C:23]2[C:19]([CH2:20][CH2:21][N:22]2[CH:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)=[CH:18][CH:17]=1>>[F:15][C:16]1[CH:24]=[C:23]2[C:19]([CH2:20][CH2:21][N:22]2[CH:25]2[CH2:30][CH2:29][N:28]([C:8]3[N:9]=[N:10][C:11]([N:4]4[CH:3]=[C:2]([CH3:1])[CH:6]=[N:5]4)=[CH:12][CH:13]=3)[CH2:27][CH2:26]2)=[CH:18][CH:17]=1Participants
4
Procedure
The title compound was prepared following the procedure as described in Example 14, reacting 4-methylpyrazole, 3,6-dichloropyridazine, and 6-fluoro-1-(piperidin-4-yl)indoline.
Sources & evidence
- ORD record
- ord-f038dab5f1804dbc83846d20ffa4bcd5
- Source dataset
- uspto-grants-2015_08
- Patent number
- US09102669B2
Reaction notes
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