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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512841Generated: October 25, 2026

3,6-Dichloropyridazine → 2-(1-(6-(4-(6-fluoroindolin-1-yl)piperidin-1-yl)pyridazin-3-yl)-1H-pyrazol-4-yl)ethanol

https://huagongshe.com/reaction/512841

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,6-DichloropyridazineHCID 67331—
Reactant2-(1H-Pyrazol-4-yl)ethanolHCID 4293604—
Reactant6-Fluoro-1-(piperidin-4-yl)indolineHCID 22038384—
Product2-(1-(6-(4-(6-fluoroindolin-1-yl)piperidin-1-yl)pyridazin-3-yl)-1H-pyrazol-4-yl)ethanolHCID 76332840—

Reaction Steps

The title compound was prepared following the procedure as described in Example 14, reacting 4-(2-hydroxyethyl)pyrazole, 3,6-dichloropyridazine, and 6-fluoro-1-(piperidin-4-yl)indoline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102669B2
Source datasetuspto-grants-2015_08
ORD IDord-a85e883783a3401bad6f51ae0ff43391
Source noteuspto-grants-2015_08