(6-Methoxypyridin-3-yl)boronic acid → HCID 76325600, compound

HRID 512859Notes

Reaction equation

HRID 512859 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6](B(O)O)=[CH:5][N:4]=1.Cl[C:13]1[N:18]=[N:17][C:16]([N:19]2[CH2:24][CH2:23][CH:22]([N:25]3[C:33]4[C:28](=[CH:29][CH:30]=[C:31]([F:34])[CH:32]=4)[CH2:27][CH2:26]3)[CH2:21][CH2:20]2)=[CH:15][CH:14]=1>>[F:34][C:31]1[CH:32]=[C:33]2[C:28]([CH2:27][CH2:26][N:25]2[CH:22]2[CH2:23][CH2:24][N:19]([C:16]3[N:17]=[N:18][C:13]([C:6]4[CH:5]=[N:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=4)=[CH:14][CH:15]=3)[CH2:20][CH2:21]2)=[CH:29][CH:30]=1

Participants

3

Reactant 2

HCID 2734368(6-Methoxypyridin-3-yl)boronic acidHCID 896144661-(1-(6-Chloropyridazin-3-yl)piperidin-4-yl)-6-fluoroindoline

Product 1

HCID 76325600HCID 76325600, compound

Procedure

The title compound was prepared following the procedure as described in Example 1, Method A, STEP 4, reacting 2-methoxypyridine-5-boronic acid and 1-(1-(6-chloropyridazin-3-yl)piperidin-4-yl)-6-fluoroindoline.

Sources & evidence

ORD record
ord-e2767f36dfff4878bfd9a424f466d712
Source dataset
uspto-grants-2015_08
Patent number
US09102669B2

Reaction notes

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