6-(Dimethylamino)pyridine-3-boronic acid → HCID 76314706, compound

HRID 512860Notes

Reaction equation

HRID 512860 reaction equation
[CH3:1][N:2]([C:4]1[CH:9]=[CH:8][C:7](B(O)O)=[CH:6][N:5]=1)[CH3:3].Cl[C:14]1[N:19]=[N:18][C:17]([N:20]2[CH2:25][CH2:24][CH:23]([N:26]3[C:34]4[C:29](=[CH:30][CH:31]=[C:32]([F:35])[CH:33]=4)[CH2:28][CH2:27]3)[CH2:22][CH2:21]2)=[CH:16][CH:15]=1>>[F:35][C:32]1[CH:33]=[C:34]2[C:29]([CH2:28][CH2:27][N:26]2[CH:23]2[CH2:24][CH2:25][N:20]([C:17]3[N:18]=[N:19][C:14]([C:7]4[CH:8]=[CH:9][C:4]([N:2]([CH3:3])[CH3:1])=[N:5][CH:6]=4)=[CH:15][CH:16]=3)[CH2:21][CH2:22]2)=[CH:30][CH:31]=1

Participants

3

Reactant 2

HCID 27632716-(Dimethylamino)pyridine-3-boronic acidHCID 896144661-(1-(6-Chloropyridazin-3-yl)piperidin-4-yl)-6-fluoroindoline

Product 1

HCID 76314706HCID 76314706, compound

Procedure

The title compound was prepared following the procedure as described in Example 1, Method A, STEP 4, reacting 2-(N,N-dimethylamino)pyridine-5-boronic acid and 1-(1-(6-chloropyridazin-3-yl)piperidin-4-yl)-6-fluoroindoline.

Sources & evidence

ORD record
ord-c44485cdca0648b7b49e4c2bc7d54dca
Source dataset
uspto-grants-2015_08
Patent number
US09102669B2

Reaction notes

Loading…