HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-(4-chlorophenyl)carbamate → (2-Amino-5-chloro-phenyl)-(2,4-difluoro-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-(4-chlorophenyl)carbamate | HCID 546372 | — |
| Reactant | 2,4-Difluorobenzoyl chloride | HCID 588081 | — |
| Product | (2-Amino-5-chloro-phenyl)-(2,4-difluoro-phenyl)-methanone | HCID 64423774 | 20% |
Reaction Steps
In a manner similar to that described above for compound 1aa, 4-Chloro-N-Boc-aniline and 2,4-difluoro-benzoyl chloride were converted to 1w (20% yield) MS m/z=268 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102678B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-58cdec6ff740401b8563bb9cd855a2ab |
| Source note | uspto-grants-2015_08 |