HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2,4-dichloropyrimidine → tert-butyl N-[2-[(5-bromo-2-chloro-pyrimidin-4-yl)amino]-2-methyl-propyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2,4-dichloropyrimidine | HCID 289973 | — |
| Reactant | tert-butyl N-(2-amino-2-methylpropyl)carbamate | HCID 17909918 | — |
| Reactant | tert-butyl N-[2-[(5-bromo-2-chloro-pyrimidin-4-yl)amino]-3-methyl-butyl]carbamate | HCID 86695593 | — |
| Product | tert-butyl N-[2-[(5-bromo-2-chloro-pyrimidin-4-yl)amino]-2-methyl-propyl]carbamate | HCID 86695601 | — |
Reaction Steps
tert-butyl N-[2-[(5-bromo-2-chloro-pyrimidin-4-yl)amino]-2-methyl-propyl]carbamate was synthesized using 5-bromo-2,4-dichloro-pyrimidine and tert-butyl N-(2-amino-2-methyl-propyl)carbamate using analogous reaction conditions as described for tert-butyl N-[2-[(5-bromo-2-chloro-pyrimidin-4-yl)amino]-3-methyl-butyl]carbamate. LCMS (ESI) 379 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102682B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-ce97d98857d04515bf8c6f40f83f56b9 |
| Source note | uspto-grants-2015_08 |