Trifluoroacetic acid → HCID 68379877, compound

Participants

Reaction Conditions

Reaction Steps

Intermediate 16 (189 mg, 0.342 mmol) and trifluoroacetic acid (0.022 mL, 0.285 mmol) were dissolved in DCM (3 mL) and stirred at 25° C. under N2 for 2 h. The solvent was evaporated under vacuum and the residue obtained dissolved in DCM and re-evaporated under vacuum to give a yellow oil which was dried under high vacuum to afford the title compound as a yellow solid (153 mg, 0.270 mmol, 95% yield). LC/MS (M(35Cl)+H)+ 453, (M(37Cl)+H)+ 455; RT 0.74 min.

Provenance & Evidence