HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Peroxide → 2-Amino-4-bromo-3-methoxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 6-Bromo-7-methoxyindoline-2,3-dione | HCID 117599994 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Amino-4-bromo-3-methoxybenzoic acid | HCID 117599761 | — |
Reaction Steps
H2O2 (37%, 7.7 mL, 0.075 mol) in H2O (70 mL) is slowly added to the solution of 6-Bromo-7-methoxy-1H-indole-2,3-dione (8.0 g, 0.0312 mol), NaOH (8.8 g, 0.219 mol) in H2O (200 mL) then stirred at room temperature for 1 hour. After reaction, the mixture is filtered and the solid is dried under vacuum to give the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102684B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-3eb192af572943b6913c4b1e06f8f538 |
| Source note | uspto-grants-2015_08 |