HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 5-Chloro-8-nitroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Potassium Nitrate | HCID 24434 | — |
| Reactant | 5-Chloroquinoline | HCID 69458 | — |
| Solvent | Dichloromethane pentane | HCID 21877063 | — |
| Product | 5-Chloro-8-nitroquinoline | HCID 242755 | 51% |
Reaction Steps
In a similar fashion using route 7 general procedure 15, 5-chloroquinoline (1.0 g, 6.13 mmol), potassium nitrate (0.8 g, 7.98 mmol) and H2SO4 (3 ml) gave the title compound (630 mg, 51%) after trituration from DCM/n-pentane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-db14921b42524c4eb26cb62c4f69a82d |
| Source note | uspto-grants-2015_08 |