Glycerol → 8-Nitro-6-(trifluoromethoxy)quinoline

関与物質

反応手順

In a similar fashion using route 10 general procedure 20, 2-nitro-4-(trifluoromethoxy)aniline (1.0 g, 4.50 mmol), glycerol (1.3 g, 13.96 mmol) and 3-nitrobenzenesulfonic acid sodium salt (1.32 g, 5.85 mmol), gave the title compound (1.1 g, 95%) which was used in the next step without purification.

情報源と証拠