HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycerol → 6-Ethoxy-8-nitroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycerol | HCID 753 | — |
| Reactant | Sodium 3-nitrobenzenesulfonate | HCID 31389 | — |
| Reactant | 4-Ethoxy-2-nitroaniline | HCID 69229 | — |
| Product | 6-Ethoxy-8-nitroquinoline | HCID 16772584 | 75.1% |
Reaction Steps
In a similar fashion using route 10 general procedure 20, 4-ethoxy-2-nitroaniline (1.0 g, 5.49 mmol), glycerol (1.6 g, 17.0 mmol) and 3-nitrobenzenesulfonic acid sodium salt (1.6 g, 7.14 mmol) gave the title compound (900 mg, 75%) which was used in the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-be2536717f0944b4848386e98ba22d9d |
| Source note | uspto-grants-2015_08 |