HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycerol → HCID 68183108, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycerol | HCID 753 | — |
| Reactant | Sodium 3-nitrobenzenesulfonate | HCID 31389 | — |
| Reactant | 4,5-Difluoro-2-nitroaniline | HCID 157151 | — |
| Reactant | Sulfuric acid hydrate (1:1) | HCID 21910475 | — |
| Product | HCID 68183108 | HCID 68183108 | 83% |
Reaction Steps
In a similar fashion using route 10 general procedure 20, 4,5-difluoro-2-nitroaniline (200 mg, 1.15 mmol), glycerol (330 mg, 3.56 mmol), 3-nitrobenzenesulfonic acid sodium salt (336 mg, 1.49 mmol) and H2SO4/H2O (1.2 ml, 7:5) gave the title compound (200 mg, 83%) after purification by column chromatography with DCM as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-607e15c5ea964d709187301cdea0f326 |
| Source note | uspto-grants-2015_08 |