HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → 6-Ethoxyquinolin-8-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | 6-Ethoxy-8-nitroquinoline | HCID 16772584 | — |
| Catalyst | Hydrochloric Acid | HCID 313 | — |
| Product | 6-Ethoxyquinolin-8-amine | HCID 19609390 | 90.3% |
Reaction Steps
In a similar fashion using route 1 general procedure 4, 6-ethoxy-8-nitroquinoline (Intermediate 35) (900 mg, 4.12 mmol), tin (II) chloride (2.4 g, 12.4 mmol) and 6 N HCl (10 drops) gave the title compound (700 mg, 90%) which was used in the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-91a61343ff3e4467ac0fedd488f87839 |
| Source note | uspto-grants-2015_08 |