HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → HCID 68183356, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | HCID 68183092 | HCID 68183092 | — |
| Catalyst | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 68183356 | HCID 68183356 | 62% |
Reaction Steps
In a similar fashion using route 1 general procedure 4, 5-chloro-6-methyl-8-nitroquinoline (Intermediate 39) (300 mg, 1.35 mmol), tin (II) chloride (760 mg, 4.05 mmol) and 6N HCl (4 drops) gave the title compound (160 mg, 62%) after purification by column chromatography with n-hexane/EtOAc (9:1) as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-ae44dfe3568c4ddb86105d73fd83da73 |
| Source note | uspto-grants-2015_08 |