HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 7-METHOXY-8-NITROQUINOLINE
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Potassium Nitrate | HCID 24434 | — |
| Reactant | 7-Methoxyquinoline | HCID 78666 | — |
| Product | 7-METHOXY-8-NITROQUINOLINE | HCID 11206492 | 50% |
Reaction Steps
In a similar fashion using route 7 general procedure 15, 7-methoxyquinoline (Intermediate 58) (400 mg, 2.51 mmol), potassium nitrate (330 mg, 3.26 mmol) and conc. H2SO4 (1.2 ml) gave the title compound (250 mg, 50%) after purification by column chromatography with n-hexane/EtOAc (3:1) as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-ae2c31661e474a0f92222bcd3eb5f09e |
| Source note | uspto-grants-2015_08 |