HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → 7-Methoxyquinolin-8-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | 7-METHOXY-8-NITROQUINOLINE | HCID 11206492 | — |
| Catalyst | Hydrochloric Acid | HCID 313 | — |
| Product | 7-Methoxyquinolin-8-amine | HCID 12849813 | 71% |
Reaction Steps
In a similar fashion using route 1 general procedure 4, 7-methoxy-8-nitroquinoline (Intermediate 61) (250 mg, 1.22 mmol), tin (II) chloride (700 mg, 3.67 mmol) and 6N HCl (3 drops) gave the title compound (150 mg, 71%) which was used in the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-8d3c1d62687d403ba18caa0a97ecb183 |
| Source note | uspto-grants-2015_08 |