HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy-8-quinolinamine → 2,4-dichloro-N-(6-methoxyquinolin-8-yl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy-8-quinolinamine | HCID 7023 | — |
| Reactant | Benzenesulfonyl chloride, 2,4-dichloro- | HCID 204419 | — |
| Product | 2,4-dichloro-N-(6-methoxyquinolin-8-yl)benzenesulfonamide | HCID 68183309 | 53% |
Reaction Steps
In a similar fashion using route 14 general procedure 26, 6-methoxyquinolin-8-amine (Intermediate 23) (60 mg, 0.35 mmol), 2,4-dichlorobenzenesulfonyl chloride (110 mg, 0.45 mmol) gave the title compound (70 mg, 53%) after purification by column chromatography with DCM as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-88ec89d508c64782a4b0587e39407198 |
| Source note | uspto-grants-2015_08 |