HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy-8-quinolinamine → Pyridine-3-sulfonic acid (6-methoxy-quinolin-8-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy-8-quinolinamine | HCID 7023 | — |
| Reactant | Pyridine-3-sulfonyl chloride | HCID 3164136 | — |
| Product | Pyridine-3-sulfonic acid (6-methoxy-quinolin-8-yl)-amide | HCID 60163924 | 39% |
Reaction Steps
In a similar fashion using route 14 general procedure 26, 6-methoxyquinolin-8-amine (Intermediate 23) (50 mg, 0.29 mmol), pyridine-3-sulfonyl chloride (Intermediate 17) (76 mg, 0.43 mmol) gave the title compound (35 mg, 39%) after purification by column chromatography with DCM as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-8f3bd99d7bc24a3f95ba815b3b0cb049 |
| Source note | uspto-grants-2015_08 |