HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride → N-(4-Methoxy-quinolin-8-yl)-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | 4-Methoxyquinolin-8-amine | HCID 12270662 | — |
| Product | N-(4-Methoxy-quinolin-8-yl)-benzenesulfonamide | HCID 68183281 | 17.1% |
Reaction Steps
In a similar fashion using route 14 general procedure 26, 4-methoxy-quinolin-8-ylamine (Intermediate 71) (71 mg, 0.41 mmol), benzenesulfonyl chloride (79 mg, 0.44 mmol) gave the title compound (22 mg, 17%) after purification by column chromatography with DCM as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-d912bd6045cb40d4b9daa7aac3ca6e15 |
| Source note | uspto-grants-2015_08 |